Synake, Syn-ake, Snake Venom Cream, Venom Cream, Viper Cream...Anti Aging Cream
PROLOU the secret ingredient - Synake
Synake is a new anti-wrinkle active compound based on a synthetic tripeptide that mimics the effect of
waglerin 1, a peptide that is found in the venom of the Temple
Viper.
The most advanced anti wrinkle cream on the market
today
Wrinkles are reduced in a short period with Synake.
Synake is particularly effective against expression lines.
Synake is an intense ageing anti-wrinkle cream.

EFFICACY TESTS
In vitro tests:
By measuring the contraction of the innervated muscle cell
as a function of the incubation time, we can demonstrate the
efficacy of the Synake tripetide in vitro, based on a 5ml
concentration.
Synake reduces muscle cell concentration and the
action is reversible.
In vivi tests:
By comparing the Synake (4%) against a placebo, it allowed
us to measure the smoothness and overall effectiveness. For
28 days the cream was applied twice daily.
Synake - Age Killing Effect.
The smoothing effect (Ra) was measured on 80% of the
volunteers and the anti-wrinkle effect (Rz, Rt) measured on
73% of the volunteers.
Results showed up to a 52% wrinkle decrease after
applying it for 28 days.
The Real "Age-Killing-Effect"
Synake: synthetic substance mimics snake venom activity
Snake venom can be deadly to humans but it can also be used
to heal. ‘Wrinkle-killer’ to help improve the facial appearance
of both men and women. Synake is a synthetic substance which
mimics part of a polypeptide found in the venom of a Temple
Viper.
When communicating such as frowning, speaking and laughing,
we us about 60 muscles in our face. Over time this causes
wrinkles in the deeper layers. But know a treatment is available
to get rid of these wrinkles without having to have cosmetic
surgery or Botox.
Synake is the alternative to using using these extremes. The
new synthetic Tripeptide mimics the effect of Waglerin-1.
The viper, from which it is found, owes its name to the German
herpe- tologist Johann Georg Wagler. He found that it inhibits
neuromuscular communication. Once the snake has bitten its
prey, the venom blocks the nerve pulses therefore paralysing
its victim. This causes death, but the synthetic imitation
which is found in Syn-ake, means part of the venom causes
the muscles contractions to relax. The end result- smooth,
replenished looking skin.
Its excellent formula reduces wrinkles and smoothes out the
surface in just a few days. The in vivo studies dealing with
crow's feet confirmed the efficiency of the product. It found
that using Syake of a concentration of 5ml, reduces the frequency
of muscle contractions in innervated muscles by up to 82%
(p<O.05) within 2hours.
Snake venom research by Pentapharm in Brazil has enabled this
unique treatment to come about and be available today. For
30 years snake venom has been used for therapeutic diagnostic
purposes. An example is the Lance Adder venom found in South
America. By utilizing the anti-coagulant parts of the snake,
Pentapharm is able to breed around 10,000 in their snake farm
in Brazil.
The venom is milked locally and then purified in Switzerland.
The production of Synake allows the snake farm to stay open
and is totally safe . Indisputably, ecology-friendly and totally
without risk, during production (in line with our "Responsible
Care Program"). It contains no preservative and is considered
absolutely safe for use in cosmetic products.
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